A daily adaptogen formulation designed to support stress modulation, mood stability, and sleep quality during menopause and perimenopause. Combines clinically studied Ashwagandha with black pepper to optimize bioavailability.
All batch testing and Certificates of Analysis are available in the Menopause Science Trust Center.
Clinical Profile
Targets
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Stress response and cortisol regulation
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Mood variability
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Sleep latency and continuity
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Nervous system support during hormonal transition
Primary Active
Organic Ashwagandha Root (Withania somnifera) — 1000 mg per serving
An adaptogenic herb shown to support stress resilience, mood stability, and sleep regulation.
Formulation Rationale
Hormonal changes and stress can disrupt mood regulation and sleep patterns. This formulation combines Ashwagandha with black pepper to enhance absorption and maximize physiological impact.
Organic Black Pepper (Piper nigrum) — Increases bioavailability of active constituents in Ashwagandha.
The formulation is designed for daily use to support multiple pathways involved in stress response, mood regulation, and sleep quality without sedation
Key Characteristics
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Clinically aligned Ashwagandha dosage
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Black pepper–enhanced absorption
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Vegan, non-GMO, gluten-free, sugar-free
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Free from artificial fillers and preservatives
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Manufactured in a GMP-certified, FDA-registered facility
Full Ingredient List
Organic Ashwagandha Root
Organic Black Pepper
Vegetable Capsule
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Trust Center Verified
Comprehensive analysis of clinical research and evidence*
Mood & Sleep Support By Menopause Science
Clinical research shows that up to 80% of perimenopausal women experience mood disturbances and sleep problems. Mood and Sleep Support provides organic ashwagandha root enhanced with black pepper extract for maximum bioavailability and effectiveness.*
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Research Summary
Clinical research suggests that ashwagandha supplementation may significantly reduce perceived stress, anxiety, and improve sleep quality while supporting healthy cortisol levels. Studies specifically in perimenopausal women suggest that ashwagandha may reduce total menopause symptom scores, with particular benefits for psychological symptoms, mood disturbances, and sleep disruption. The addition of black pepper extract (piperine) may enhance absorption, potentially ensuring optimal therapeutic benefits.*
Research at a Glance
|
Ingredient |
Population Studied |
Studied Benefit(s) |
Research Link |
|
Ashwagandha (600mg daily) |
100 perimenopausal women aged 45-60 |
8-week RCT: Significant reduction in total menopause symptoms, anxiety, irritability, and depressive symptoms vs placebo |
View Study |
|
Ashwagandha (300mg 2x daily) |
64 adults with chronic stress |
60-day RCT: 44% reduction in stress scores, significant reduction in anxiety and cortisol levels |
View Study |
|
Ashwagandha (240mg daily) |
60 stressed adults |
60-day RCT: Significant reduction in anxiety (HAM-A scale) and morning cortisol levels vs placebo |
View Study |
|
Ashwagandha |
400 participants across 5 studies |
Meta-analysis: Significant improvement in overall sleep quality, sleep onset latency, and total sleep time |
View Study |
|
Ashwagandha (300mg 2x daily) |
60 insomnia patients |
10-week RCT: Significant improvement in sleep onset latency, sleep efficiency, and quality vs placebo |
View Study |
|
Black Pepper (Piperine) |
Various supplement studies |
Bioavailability enhancer: Increases absorption of herbal compounds by inhibiting liver enzymes |
View Study |

